THE POLO CLINICAL RESEARCH STUDY IS NOW ENROLLING PEDIATRIC PATIENTS WITH IRRITABLE BOWEL SYNDROME WITH CONSTIPATION

Physicians across the nation are pleased to announce that the Polo Clinical Research Study is now enrolling pediatric patients with Irritable Bowel Syndrome with Constipation at 50 participating locations in the US.

Pediatric Irritable Bowel Syndrome (IBS) is a frequent problem. Studies have reported IBS in up to 16% of children between the ages of 11 and 17.1 Constipation is the most common subtype.2

Children suffering from Irritable Bowel Syndrome with Constipation (IBS-C) experience abdominal pain that sometimes resolves after completing a bowel movement. These children may also experience a change in the frequency or appearance of their bowel movements with the onset of pain. Additionally, they have 2 or fewer bowel movements per week. Affected children may actively try to stop their bowel movements.

This new clinical research study will evaluate the investigational use in children of a study drug that has already been approved by the FDA to treat adults with symptoms of constipation. Physicians are currently enrolling the Polo Clinical Research Study for patients aged 7 – 17 who have IBS-C and who, for at least the past 2 months, have had 2 or fewer bowel movements each week and may actively try to stop their bowel movements or exhibit retentive posturing where they stand straight, on their toes, or have a red face as they try to stop their bowel movements. Additionally, children must have had abdominal pain or discomfort with bowel movements at least sometimes for the last 2 months.

For more information and to learn about additional eligibility criteria, please contact 1-888-609-3456 or additional information is available at www.marco-polostudies.com .

1. El-Baba MD, et al., http://emedicine.medscape.com/article/930844-overview#showall

2. Giannetti E, et al. Subtypes of irritable bowel syndrome in children: prevalence at diagnosis and at follow-up. J. Pediatr. 2014. 164:1099-1103.

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