Neighbor News
Understanding T Cells Used for COVID-19 Vaccine Development
Scientists working hard to develop antigen-specific T cell line to fight SARS-CoV-2, the virus that causes COVID-19.
Our scientists are focused on developing an antigen-specific T cell line directed against the spike protein of SARS-CoV-2, the virus that causes COVID-19.
Preliminary studies, including this one in Cell, suggest a T cell defense against COVID-19 found in infected individuals and in those not known to be infected — likely from a previous infection of another coronavirus.
In Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals, Grifoni et al. describe:
Find out what's happening in Seattlefor free with the latest updates from Patch.
- Measuring immunity to SARS-CoV-2 is key to understanding COVID-19 and vaccine development
- Epitope pools detect CD4+ and CD8+ T cells in 100% and 70% of convalescent COVID patients
- T cell responses are focused not only on spike but also on M, N, and other ORFs
- T cell reactivity to SARS-CoV-2 epitopes is also detected in non-exposed individuals
This post originally appeared on the Cellero blog and has been modified for Patch.