Montgomery County Community College: National Science Foundation Awards $573,347 Grant To College

Press release from the Montgomery County Community College:

Eric Devlin

April 21, 2021

The workforce that could one day help develop and manufacture the advanced, life-saving
medicines of tomorrow may soon find themselves inside a Montgomery County Community
College (MCCC) classroom learning the tools of the trade, thanks to a new grant from
the National Science Foundation (NSF).

The NSF has awarded a $573,347 grant to the College to support MCCC’s efforts to build
Southeastern Pennsylvania's advanced technical workforce for the cell and gene therapy
industry.

The rapidly growing industry of cell and gene therapy holds great promise in the treatment
of diseases such as cancer and inherited genetic disorders. Unlike chemical drugs
or biopharmaceuticals like insulin, which are delivered into the body to combat illnesses,
gene and cell therapies are the next generation of medical research and practice in
that they focus on modifying a patient’s own cells or genes to help the body combat
a disease on its own.

Pharmaceutical companies, including giants like Merck and GlaxoSmithKline, have expressed a need for trained and motivated staff in gene and cell therapies from many disciplines
including bioscience, chemistry and engineering, all working together to make these
medicines a reality for the hundreds of thousands of patients who could potentially
benefit. With the increased approval of these types of therapies in recent years,
there will be an increasing demand for professionals for these companies.

Biotechnology Associate Professor Dr. Margaret Bryans, who wrote the NSF grant application,
is the grant’s principal investigator and Dr. James Bretz, Dean of Science, Technology,
Engineering and Mathematics (STEM) is the co-principal investigator. Bryans explained
the Philadelphia region has quickly become a hub for cell and gene therapy.

“It has been referred to as ‘Cellicon Valley’ because of the growth of these companies
in the Philadelphia region,” said Dr. Bryans. “There are about 30 companies developing
cell or gene therapies as well as numerous contract manufacturing organizations, contract
research organizations and big pharma companies also working on these advanced therapies.

Bryans states the importance of training the workforce needed to meet the growing
demand to ensure companies will continue to invest in the Philadelphia region.

“There are over 1,000 cell and gene therapy products in clinical trials worldwide,”
she said, “with the potential for the field to grow exponentially. There’s going to
be a shortage of skilled technicians to develop, manufacture and test these products.”

“This grant is designed to provide trained technicians with the involvement of industry
partners,” said Bretz. “It’s built off of Dr. Bryans’ great work on previous grants
and programs at the college.”

The NSF grant will help the College accomplish three goals: to develop new curriculum
for an associate’s degree program and a new certificate in advanced therapies; facilitate
other regional colleges and institutions to develop and offer their own cell and gene
therapy courses and programs; and begin to engage high school students to consider
a career in the field of cell and gene therapy through summer programming at MCCC,
said Bryans.

“It’s an interesting, rewarding, and well-paid career,” said Bryans. “The summer program
will create an awareness through a one-week biotechnology experience. We’ll be recruiting
high school and middle school students from underrepresented populations. Each year
16 students will learn about the field, perform lab experiments and hear from industry-scientists
firsthand. It will help put them on educational paths toward an associate’s degree,
to a bachelor’s degree and then to a master’s degree and beyond. It will offer a chance
to give real world insight into this important field and what it takes to be part
of it.”

MCCC currently offers two Biotechnology programs of study, a two year Associate in Applied Science degree in Biotechnology
and a one year Certificate in Biotechnology and Biomanufacturing designed for degree-holding students who wish to acquire the lab skills and knowledge
needed to enter the biotechnology workforce.

MCCC President Dr. Victoria L. Bastecki-Perez applauded Bryans and Bretz’s efforts.

“Dr. Bryans’ work is transformational for our students,” she said. “Being in the company
of schools like the University of Pennsylvania, leading research and development in
this field, and training our students for living-wage jobs is extraordinary. I am
immensely proud of our collective work to ensure a brighter future for all.”

Dr. Bryans is no stranger to the grant process. She has been the recipient of several
grants from the National Science Foundation. Over a 10-year period, the NSF has granted
over $10 million (including its most recent grant of $2.6 million in 2016) to the
Northeast Biomanufacturing Center and Collaborative (NBC2), a consortium of six community colleges that work collaboratively to mentor programs,
design curriculum and provide training opportunities for technicians for the biomanufacturing
industry. At MCCC, Bryans has developed open-source curriculum and training workshops
for community college instructors, as well as summer workshops for area high school
teachers and programs for students to introduce them to careers in biomanufacturing.

This press release was produced by the Montgomery County Community College. The views expressed here are the author’s own.